The following organizations are members of the SD Cancer Coalition:
Member organizations as of April 2023
- American Cancer Society
- Avera Cancer Institutes
- Avera Health
- Black Hills Center for American Indian Health
- Black Hills Special Services Cooperative
- Cheyenne River Sioux Tribe Breast & Cervical Cancer Early Detection Program
- Community HealthCare Association of the Dakotas
- Delta Dental
- Exact Sciences
- Falls Community Health
- Great Plains Quality Innovation Network
- Great Plains Tribal Chairmen’s Health Board
- HealthPOINT
- Helpline Center
- Horizon Healthcare
- Immunize SD
- Indian Health Service
- Pfizer
- Rapid City Medical Center
- Rapid City Regional
- Sanford Cancer Center
- Sanford Health
- Sanford School of Medicine USD
- Sioux Falls School District
- Siouxland Oral & Maxillofacial Surgery
- SLM Consulting, LLC
- South Dakota Association of Healthcare Organizations
- South Dakota Academy of Family Physicians
- South Dakota Department of Health
- South Dakota Legislature
- South Dakota State Medical Association
- South Dakota State University
- Susan G. Komen Great Plains
- University of South Dakota
- Volunteers of America, Dakotas
- Walking Forward
- Yankton Rural AHEC